News & Publications

News & Publications


Proteogenomic-based discovery of minor histocompatibility antigens with suitable features for immunotherapy of hematologic cancers. Granados DP, Rodenbrock A, Laverdure J-P, Côté C, Caron-Lizotte O, Carli C, Pearson H, Janelle V, Durette C, Bonneil E, Roy DC, Delisle J-S, Lemieux S, Thibault P and Perreault C. Leukemia (2016) 30, 1344-1354; doi:10.1038/leu.2016.22.

Global proteogenomic analysis of human MHC class I-associated peptides derived from non-canonical reading frames. Laumont CM, Daouda T, Laverdure JP, Bonneil É, Caron-Lizotte O, Hardy MP, Granados DP, Durette C, Lemieux S, Thibault P and Perreault C. Nat Commun. 2016 Jan 5;7:10238. doi: 10.1038/ncomms10238.

Defining novel parameters for the optimal priming and expansion of minor histocompatibility antigen-specific T cells in culture. Janelle V, Carli C, Taillefer J, Orio J and Delisle JS. J Transl Med. 2015 April 19;13:123. doi: 10.1186/s12967-015-0495-z.

Impact of genomic polymorphisms on the repertoire of human MHC class I-associated peptides. Granados DP, Sriranganadane D, Daouda T, Zieger A, Laumont CM, Caron-Lizotte O, Boucher G, Hardy MP, Gendron P, Côté C, Lemieux S, Thibault P and Perreault C. Nat Commun. 2014 Apr 9;5:3600. doi: 10.1038/ncomms4600.

Rejection of leukemic cells requires antigen-specific T cells with high functional avidity. Vincent K, Hardy MP, Trofimov A, Laumont CM, Sriranganadane D, Hadj-Mimoune S, Salem Fourati I, Soudeyns H, Thibault P and Perreault C. Biol Blood Marrow Transplant. 2014 Jan; 20(1):37-45. doi: 10.1016/j.bbmt.2013.10.020. Epub 2013 Oct 23, PMID: 24161924 [PubMed - indexed for MEDLINE]

The TGF-ß-Smad3 pathway inhibits CD28-dependent cell growth and proliferation of CD4 T cells. Delisle JS, Giroux M, Boucher G, Landry JR, Hardy MP, Lemieux S, Jones RG, Wilhelm BT and Perreault C. Genes Immun. 2013 Mar;14(2): 115-26. doi: 10.1038/gene.2012.63. Epub 2013 Jan 17.

MHC I-associated peptides preferentially derive from transcripts bearing miRNA response elements. Granados DP, Yahyaoui W, Laumont CM, Daouda T, Muratore-Schroeder TL, Côté C, Laverdure JP, Lemieux S, Thibault P and Perreault C. Blood. 2012 Jun 28;119(26):e181-91. doi: 10.1182/blood-2012-02-412593. Epub 2012 Mar 21.

Origin and plasticity of MHC I-associated self peptides. de Verteuil D, Granados DP, Thibault P and Perreault C. Autoimmun Rev. 2012 Jul; 11(9): 627-35. doi: 10.1016/j.autrev.2011.11.003. Epub 2011 Nov 12. Review.

The MHC I immunopeptidome conveys to the cell surface an integrative view of cellular regulation. Caron E, Vincent K, Fortier MH, Laverdure JP, Bramoullé A, Hardy MP, Voisin G, Roux PP, Lemieux S, Thibault P and Perreault C. Mol Syst Biol. 2011 Sep 27;7:533. doi: 10.1038/msb.2011.68.

Next-generation leukemia immunotherapy. Vincent K, Roy DC and Perreault C. Blood. 2011 Sep 15;118(11):2951-9. doi:10.1182/blood-2011-04-350868. Epub 2011 Jul 6. Review.

SMAD3 prevents graft-versus-host disease by restraining Th1 differentiation and granulocyte-mediated tissue damage. Giroux M, Delisle JS, Gauthier SD, Heinonen KM, Hinsinger J, Houde B, Gaboury L, Brochu S, Wu J, Hébert MJ and Perreault C. Blood. 2011 Feb 3;117(5): 1734-44. doi:10.1182/blood-2010-05-287649. Epub 2010 Nov 30.

The origin and role of MHC class I-associated self-peptides. Perreault C. Prog Mol Biol Transl Sci. 2010;92:41-60. doi: 10.1016/S1877-1173(10)92003-6.

Prediction of graft-versus-host disease in humans by donor gene-expression profiling. Baron C, Somogyi R, Greller LD, Rineau V, Wilkinson P, Cho CR, Cameron MJ, Kelvin DJ, Chagnon P, Roy DC, Busque L, Sékaly RP and Perreault C. PLoS Med. 2007 Jan;4(1):e23.